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PKCε Phosphorylates and Mediates the Cell Membrane Localization of RhoA

Protein kinase Cε (PKCε) signals through RhoA to modulate cell invasion and motility. In this study, the multifaceted interaction between PKCε and RhoA was defined. Phosphopeptide mapping revealed that PKCε phosphorylates RhoA at T127 and S188. Recombinant PKCε bound to recombinant RhoA in the absen...

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Detalles Bibliográficos
Autores principales:	Su, Tizhi, Straight, Samuel, Bao, Liwei, Xie, Xiujie, Lehner, Caryn L., Cavey, Greg S., Teknos, Theodoros N., Pan, Quintin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804392/ https://www.ncbi.nlm.nih.gov/pubmed/24191200 http://dx.doi.org/10.1155/2013/329063

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