Cargando…
First Evidence of Simultaneous Circulation of Three Different Dengue Virus Serotypes in Africa
Gabon, in Central Africa, was affected for the first time in 2007 and then in 2010 by simultaneous outbreaks of chikungunya and Dengue serotype 2 (DENV-2) viruses. Through the national surveillance of dengue-like syndromes between 2007 and 2010, we observed continuous circulation of DENV-2 in a sout...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804462/ https://www.ncbi.nlm.nih.gov/pubmed/24205075 http://dx.doi.org/10.1371/journal.pone.0078030 |
_version_ | 1782288149445083136 |
---|---|
author | Caron, Melanie Grard, Gilda Paupy, Christophe Mombo, Illich Mamfred Bikie Bi Nso, Branly Kassa Kassa, Fabrice Roland Nkoghe, Dieudonne Leroy, Eric Maurice |
author_facet | Caron, Melanie Grard, Gilda Paupy, Christophe Mombo, Illich Mamfred Bikie Bi Nso, Branly Kassa Kassa, Fabrice Roland Nkoghe, Dieudonne Leroy, Eric Maurice |
author_sort | Caron, Melanie |
collection | PubMed |
description | Gabon, in Central Africa, was affected for the first time in 2007 and then in 2010 by simultaneous outbreaks of chikungunya and Dengue serotype 2 (DENV-2) viruses. Through the national surveillance of dengue-like syndromes between 2007 and 2010, we observed continuous circulation of DENV-2 in a southward movement. This rapid spread of DENV-2 was associated with the emergence of DENV-1 in 2007 and DENV-3 in 2010. Interestingly, we detected six DENV-2 infected patients with hemorrhagic signs during the second outbreak in 2010. Although these cases do not meet all standard WHO criteria for severe Dengue with hemorrhage (formerly DHF), this is the first report of several dengue fever cases associated with hemorrhagic signs during a simultaneous circulation of different DENV serotypes in Africa. Together, these findings suggest that DENV is becoming more widely established on this continent and that DHF will likely become a serious public-health problem in the near future. |
format | Online Article Text |
id | pubmed-3804462 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-38044622013-11-07 First Evidence of Simultaneous Circulation of Three Different Dengue Virus Serotypes in Africa Caron, Melanie Grard, Gilda Paupy, Christophe Mombo, Illich Mamfred Bikie Bi Nso, Branly Kassa Kassa, Fabrice Roland Nkoghe, Dieudonne Leroy, Eric Maurice PLoS One Research Article Gabon, in Central Africa, was affected for the first time in 2007 and then in 2010 by simultaneous outbreaks of chikungunya and Dengue serotype 2 (DENV-2) viruses. Through the national surveillance of dengue-like syndromes between 2007 and 2010, we observed continuous circulation of DENV-2 in a southward movement. This rapid spread of DENV-2 was associated with the emergence of DENV-1 in 2007 and DENV-3 in 2010. Interestingly, we detected six DENV-2 infected patients with hemorrhagic signs during the second outbreak in 2010. Although these cases do not meet all standard WHO criteria for severe Dengue with hemorrhage (formerly DHF), this is the first report of several dengue fever cases associated with hemorrhagic signs during a simultaneous circulation of different DENV serotypes in Africa. Together, these findings suggest that DENV is becoming more widely established on this continent and that DHF will likely become a serious public-health problem in the near future. Public Library of Science 2013-10-21 /pmc/articles/PMC3804462/ /pubmed/24205075 http://dx.doi.org/10.1371/journal.pone.0078030 Text en © 2013 Caron et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Caron, Melanie Grard, Gilda Paupy, Christophe Mombo, Illich Mamfred Bikie Bi Nso, Branly Kassa Kassa, Fabrice Roland Nkoghe, Dieudonne Leroy, Eric Maurice First Evidence of Simultaneous Circulation of Three Different Dengue Virus Serotypes in Africa |
title | First Evidence of Simultaneous Circulation of Three Different Dengue Virus Serotypes in Africa |
title_full | First Evidence of Simultaneous Circulation of Three Different Dengue Virus Serotypes in Africa |
title_fullStr | First Evidence of Simultaneous Circulation of Three Different Dengue Virus Serotypes in Africa |
title_full_unstemmed | First Evidence of Simultaneous Circulation of Three Different Dengue Virus Serotypes in Africa |
title_short | First Evidence of Simultaneous Circulation of Three Different Dengue Virus Serotypes in Africa |
title_sort | first evidence of simultaneous circulation of three different dengue virus serotypes in africa |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804462/ https://www.ncbi.nlm.nih.gov/pubmed/24205075 http://dx.doi.org/10.1371/journal.pone.0078030 |
work_keys_str_mv | AT caronmelanie firstevidenceofsimultaneouscirculationofthreedifferentdenguevirusserotypesinafrica AT grardgilda firstevidenceofsimultaneouscirculationofthreedifferentdenguevirusserotypesinafrica AT paupychristophe firstevidenceofsimultaneouscirculationofthreedifferentdenguevirusserotypesinafrica AT momboillichmamfred firstevidenceofsimultaneouscirculationofthreedifferentdenguevirusserotypesinafrica AT bikiebinsobranly firstevidenceofsimultaneouscirculationofthreedifferentdenguevirusserotypesinafrica AT kassakassafabriceroland firstevidenceofsimultaneouscirculationofthreedifferentdenguevirusserotypesinafrica AT nkoghedieudonne firstevidenceofsimultaneouscirculationofthreedifferentdenguevirusserotypesinafrica AT leroyericmaurice firstevidenceofsimultaneouscirculationofthreedifferentdenguevirusserotypesinafrica |