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Type V Collagen Induced Tolerance Suppresses Collagen Deposition, TGF-β and Associated Transcripts in Pulmonary Fibrosis
RATIONALE: Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease characterized by progressive scarring and matrix deposition. Recent reports highlight an autoimmune component in IPF pathogenesis. We have reported anti-col(V) immunity in IPF patients. The objective of our study was...
Autores principales: | Vittal, Ragini, Mickler, Elizabeth A., Fisher, Amanda J., Zhang, Chen, Rothhaar, Katia, Gu, Hongmei, Brown, Krista M., Emtiazdjoo, Amir, Lott, Jeremy M., Frye, Sarah B., Smith, Gerald N., Sandusky, George E., Cummings, Oscar W., Wilkes, David S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804565/ https://www.ncbi.nlm.nih.gov/pubmed/24204629 http://dx.doi.org/10.1371/journal.pone.0076451 |
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