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Secreted Protein Acidic and Rich in Cysteine (SPARC) Exacerbates Colonic Inflammatory Symptoms in Dextran Sodium Sulphate-Induced Murine Colitis

BACKGROUND: Secreted Protein Acidic and Rich in Cysteine (SPARC) is expressed during tissue repair and regulates cellular proliferation, migration and cytokine expression. The aim was to determine if SPARC modifies intestinal inflammation. METHODS: Wild-type (WT) and SPARC-null (KO) mice received 3%...

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Detalles Bibliográficos
Autores principales:	Ng, Yoke-Leng, Klopcic, Borut, Lloyd, Frances, Forrest, Cynthia, Greene, Wayne, Lawrance, Ian C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804578/ https://www.ncbi.nlm.nih.gov/pubmed/24204877 http://dx.doi.org/10.1371/journal.pone.0077575

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