Cargando…

A gene responsible for prolyl-hydroxylation of moss-produced recombinant human erythropoietin

Recombinant production of pharmaceutical proteins is crucial, not only for personalized medicine. While most biopharmaceuticals are currently produced in mammalian cell culture, plant-made pharmaceuticals gain momentum. Post-translational modifications in plants are similar to those in humans, howev...

Descripción completa

Detalles Bibliográficos
Autores principales:	Parsons, Juliana, Altmann, Friedrich, Graf, Manuela, Stadlmann, Johannes, Reski, Ralf, Decker, Eva L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804855/ https://www.ncbi.nlm.nih.gov/pubmed/24145658 http://dx.doi.org/10.1038/srep03019

Ejemplares similares

Glyco-engineering for biopharmaceutical production in moss bioreactors
por: Decker, Eva L., et al.
Publicado: (2014)

Moss‐made pharmaceuticals: from bench to bedside
por: Reski, Ralf, et al.
Publicado: (2015)

O-methylated N-glycans Distinguish Mosses from Vascular Plants
por: Stenitzer, David, et al.
Publicado: (2022)

Process Engineering of Biopharmaceutical Production in Moss Bioreactors via Model-Based Description and Evaluation of Phytohormone Impact
por: Ruiz-Molina, Natalia, et al.
Publicado: (2022)

Recombinant Production of MFHR1, A Novel Synthetic Multitarget Complement Inhibitor, in Moss Bioreactors
por: Top, Oguz, et al.
Publicado: (2019)

High contents of very long-chain polyunsaturated fatty acids in different moss species
por: Beike, Anna K., et al.
Publicado: (2013)

Use of endogenous signal sequences for transient production and efficient secretion by moss (Physcomitrella patens) cells
por: Schaaf, Andreas, et al.
Publicado: (2005)

Role of prolyl hydroxylation in the molecular interactions of collagens
por: Rappu, Pekka, et al.
Publicado: (2019)

Expression of a human cDNA in moss results in spliced mRNAs and fragmentary protein isoforms
por: Top, Oguz, et al.
Publicado: (2021)

Structural modelling of human complement FHR1 and two of its synthetic derivatives provides insight into their in-vivo functions
por: Ruiz-Molina, Natalia, et al.
Publicado: (2023)

Differential Effects of Collagen Prolyl 3-Hydroxylation on Skeletal Tissues
por: Homan, Erica P., et al.
Publicado: (2014)

Origin and function of stomata in the moss Physcomitrella patens
por: Chater, Caspar C., et al.
Publicado: (2016)

Correction: Differential Effects of Collagen Prolyl 3-Hydroxylation on Skeletal Tissues
Publicado: (2014)

Hydroxylation of recombinant human collagen type I alpha 1 in transgenic maize co-expressed with a recombinant human prolyl 4-hydroxylase
por: Xu, Xing, et al.
Publicado: (2011)

Prolyl hydroxylase inhibitor desidustat improves anemia in erythropoietin hyporesponsive state
por: Joharapurkar, Amit A., et al.
Publicado: (2022)

Plasma Membrane-Targeted PIN Proteins Drive Shoot Development in a Moss
por: Bennett, Tom A., et al.
Publicado: (2014)

Auxin-binding proteins without KDEL sequence in the moss Funaria hygrometrica
por: Panigrahi, Kishore C. S., et al.
Publicado: (2009)

Clonal in vitro propagation of peat mosses (Sphagnum L.) as novel green resources for basic and applied research
por: Beike, Anna K., et al.
Publicado: (2014)

Identification and characterization of NAGNAG alternative splicing in the moss Physcomitrella patens
por: Sinha, Rileen, et al.
Publicado: (2010)

Neuronal apoptosis by prolyl hydroxylation: implication in nervous system tumours and the Warburg conundrum
por: Schlisio, Susanne
Publicado: (2009)

A sequence-anchored genetic linkage map for the moss, Physcomitrella patens
por: Kamisugi, Yasuko, et al.
Publicado: (2008)

Analytical and Functional Aspects of Antibody Sialylation
por: Stadlmann, Johannes, et al.
Publicado: (2010)

Protein encoding genes in an ancient plant: analysis of codon usage, retained genes and splice sites in a moss, Physcomitrella patens
por: Rensing, Stefan A, et al.
Publicado: (2005)

PHD3-mediated prolyl hydroxylation of nonmuscle actin impairs polymerization and cell motility
por: Luo, Weibo, et al.
Publicado: (2014)

Cold sensitivity of TRPA1 is unveiled by the prolyl hydroxylation blockade-induced sensitization to ROS
por: Miyake, Takahito, et al.
Publicado: (2016)

An ancient genome duplication contributed to the abundance of metabolic genes in the moss Physcomitrella patens
por: Rensing, Stefan A, et al.
Publicado: (2007)

System for Stable β-Estradiol-Inducible Gene Expression in the Moss Physcomitrella patens
por: Kubo, Minoru, et al.
Publicado: (2013)

Stable Protein Sialylation in Physcomitrella
por: Bohlender, Lennard L., et al.
Publicado: (2020)

Cytoprotective Effect of Recombinant Human Erythropoietin Produced in Transgenic Tobacco Plants
por: Kittur, Farooqahmed S., et al.
Publicado: (2013)

Erratum to: An ancient genome duplication contributed to the abundance of metabolic genes in the moss Physcomitrella patens
por: Rensing, Stefan A., et al.
Publicado: (2016)

Comparison of Oral Recombinant Erythropoietin and Subcutaneous Recombinant Erythropoietin in Prevention of Anemia of Prematurity
por: Saeidi, R, et al.
Publicado: (2012)

Role of the Skp1 prolyl-hydroxylation/glycosylation pathway in oxygen dependent submerged development of Dictyostelium
por: Xu, Yuechi, et al.
Publicado: (2012)

2-Oxoglutarate regulates binding of hydroxylated hypoxia-inducible factor to prolyl hydroxylase domain 2
por: Abboud, Martine I., et al.
Publicado: (2018)

Cellular stress due to impairment of collagen prolyl hydroxylation complex is rescued by the chaperone 4-phenylbutyrate
por: Besio, Roberta, et al.
Publicado: (2019)

The response to unfolded protein is involved in osmotolerance of Pichia pastoris
por: Dragosits, Martin, et al.
Publicado: (2010)

Simultaneous isolation of pure and intact chloroplasts and mitochondria from moss as the basis for sub-cellular proteomics
por: Lang, Erika G. E., et al.
Publicado: (2010)

Comprehensive Mapping and Dynamics of Site-Specific Prolyl-Hydroxylation, Lysyl-Hydroxylation and Lysyl O-Glycosylation of Collagens Deposited in ECM During Zebrafish Heart Regeneration
por: Sarohi, Vivek, et al.
Publicado: (2022)

Identification of genic moss SSR markers and a comparative analysis of twenty-four algal and plant gene indices reveal species-specific rather than group-specific characteristics of microsatellites
por: von Stackelberg, Mark, et al.
Publicado: (2006)

Selfing in Haploid Plants and Efficacy of Selection: Codon Usage Bias in the Model Moss Physcomitrella patens
por: Szövényi, Péter, et al.
Publicado: (2017)

Insights on the Evolution of Prolyl 3-Hydroxylation Sites from Comparative Analysis of Chicken and Xenopus Fibrillar Collagens
por: Hudson, David M., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_3ku1mckg3usqj8uram8ndfj26d