SGOL1 variant B induces abnormal mitosis and resistance to taxane in non-small cell lung cancers

Mitosis is the most conspicuous cell cycle phase and Shugoshin-like 1 (SGOL1) is a key protein in protecting sister chromatids from precocious separation during mitosis. We studied the role of SGOL1 and its splice variants in non-small cell lung cancer (NSCLC) using 82 frozen NSCLC tissue samples. S...

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Detalles Bibliográficos
Autores principales: Matsuura, Shun, Kahyo, Tomoaki, Shinmura, Kazuya, Iwaizumi, Moriya, Yamada, Hidetaka, Funai, Kazuhito, Kobayashi, Jun, Tanahashi, Masayuki, Niwa, Hiroshi, Ogawa, Hiroshi, Takahashi, Takashi, Inui, Naoki, Suda, Takafumi, Chida, Kingo, Watanabe, Yoshinori, Sugimura, Haruhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804856/
https://www.ncbi.nlm.nih.gov/pubmed/24146025
http://dx.doi.org/10.1038/srep03012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804856/
https://www.ncbi.nlm.nih.gov/pubmed/24146025
http://dx.doi.org/10.1038/srep03012

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