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Transcription factor Runx2 controls the development and migration of plasmacytoid dendritic cells

Plasmacytoid dendritic cells (pDCs) rapidly produce type I interferon (IFN-I) in response to viruses and are essential for antiviral immune responses. Although related to classical DCs (cDCs) in their development and expression profile, pDCs possess many distinct features. Unlike cDCs, pDCs develop...

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Detalles Bibliográficos
Autores principales: Sawai, Catherine M., Sisirak, Vanja, Ghosh, Hiyaa S., Hou, Esther Z., Ceribelli, Michele, Staudt, Louis M., Reizis, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804932/
https://www.ncbi.nlm.nih.gov/pubmed/24101375
http://dx.doi.org/10.1084/jem.20130443