Recognition of gut microbiota by NOD2 is essential for the homeostasis of intestinal intraepithelial lymphocytes

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NOD2 functions as an intracellular sensor for microbial pathogen and plays an important role in epithelial defense. The loss-of-function mutation of NOD2 is strongly associated with human Crohn’s disease (CD). However, the mechanisms of how NOD2 maintains the intestinal homeostasis and regulates the...

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Detalles Bibliográficos
Autores principales: Jiang, Wei, Wang, Xiaqiong, Zeng, Benhua, Liu, Lei, Tardivel, Aubry, Wei, Hong, Han, Jiahuai, MacDonald, H. Robson, Tschopp, Jurg, Tian, Zhigang, Zhou, Rongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804938/
https://www.ncbi.nlm.nih.gov/pubmed/24062413
http://dx.doi.org/10.1084/jem.20122490

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