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RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA

Recognition of DNA and RNA molecules derived from pathogens or self-antigen is one way the mammalian immune system senses infection and tissue damage. Activation of immune signaling receptors by nucleic acids is controlled by limiting the access of DNA and RNA to intracellular receptors, but the mec...

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Detalles Bibliográficos
Autores principales: Sirois, Cherilyn M., Jin, Tengchuan, Miller, Allison L., Bertheloot, Damien, Nakamura, Hirotaka, Horvath, Gabor L., Mian, Abubakar, Jiang, Jiansheng, Schrum, Jacob, Bossaller, Lukas, Pelka, Karin, Garbi, Natalio, Brewah, Yambasu, Tian, Jane, Chang, ChewShun, Chowdhury, Partha S., Sims, Gary P., Kolbeck, Roland, Coyle, Anthony J., Humbles, Alison A., Xiao, T. Sam, Latz, Eicke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804942/
https://www.ncbi.nlm.nih.gov/pubmed/24081950
http://dx.doi.org/10.1084/jem.20120201