Molecular analysis of transplant rejection: marching onward

Transcriptional profiling of organ transplants is increasingly defining the biological pathways responsible for graft rejection at the molecular level and identifying gene transcripts that diagnose or predict rejection. These advances hold significant promise for the treatment of organ rejection and...

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Detalles Bibliográficos
Autores principales: Lakkis, Fadi G., Billiar, Timothy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804945/
https://www.ncbi.nlm.nih.gov/pubmed/24145950
http://dx.doi.org/10.1084/jem.20131810
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author Lakkis, Fadi G.
Billiar, Timothy R.
author_facet Lakkis, Fadi G.
Billiar, Timothy R.
author_sort Lakkis, Fadi G.
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description Transcriptional profiling of organ transplants is increasingly defining the biological pathways responsible for graft rejection at the molecular level and identifying gene transcripts that diagnose or predict rejection. These advances hold significant promise for the treatment of organ rejection and for improving clinical outcomes after transplantation, but hurdles remain.
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spelling pubmed-38049452014-04-21 Molecular analysis of transplant rejection: marching onward Lakkis, Fadi G. Billiar, Timothy R. J Exp Med Minireview Transcriptional profiling of organ transplants is increasingly defining the biological pathways responsible for graft rejection at the molecular level and identifying gene transcripts that diagnose or predict rejection. These advances hold significant promise for the treatment of organ rejection and for improving clinical outcomes after transplantation, but hurdles remain. The Rockefeller University Press 2013-10-21 /pmc/articles/PMC3804945/ /pubmed/24145950 http://dx.doi.org/10.1084/jem.20131810 Text en © 2013 Lakkis and Billiar This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Minireview
Lakkis, Fadi G.
Billiar, Timothy R.
Molecular analysis of transplant rejection: marching onward
title Molecular analysis of transplant rejection: marching onward
title_full Molecular analysis of transplant rejection: marching onward
title_fullStr Molecular analysis of transplant rejection: marching onward
title_full_unstemmed Molecular analysis of transplant rejection: marching onward
title_short Molecular analysis of transplant rejection: marching onward
title_sort molecular analysis of transplant rejection: marching onward
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804945/
https://www.ncbi.nlm.nih.gov/pubmed/24145950
http://dx.doi.org/10.1084/jem.20131810
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