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Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndrome

Richter syndrome (RS) derives from the rare transformation of chronic lymphocytic leukemia (CLL) into an aggressive lymphoma, most commonly of the diffuse large B cell lymphoma (DLBCL) type. The molecular pathogenesis of RS is only partially understood. By combining whole-exome sequencing and copy-n...

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Detalles Bibliográficos
Autores principales:	Fabbri, Giulia, Khiabanian, Hossein, Holmes, Antony B., Wang, Jiguang, Messina, Monica, Mullighan, Charles G., Pasqualucci, Laura, Rabadan, Raul, Dalla-Favera, Riccardo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804949/ https://www.ncbi.nlm.nih.gov/pubmed/24127483 http://dx.doi.org/10.1084/jem.20131448

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