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Calcitonin gene–related peptide inhibits Langerhans cell–mediated HIV-1 transmission

Upon its mucosal entry, human immunodeficiency virus type 1 (HIV-1) is internalized by Langerhans cells (LCs) in stratified epithelia and transferred locally to T cells. In such epithelia, LCs are in direct contact with peripheral neurons secreting calcitonin gene–related peptide (CGRP). Although CG...

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Detalles Bibliográficos
Autores principales: Ganor, Yonatan, Drillet-Dangeard, Anne-Sophie, Lopalco, Lucia, Tudor, Daniela, Tambussi, Giuseppe, Delongchamps, Nicolas Barry, Zerbib, Marc, Bomsel, Morgane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804954/
https://www.ncbi.nlm.nih.gov/pubmed/24081951
http://dx.doi.org/10.1084/jem.20122349