PI(3)P-bound UVRAG coordinates Golgi-ER retrograde and Atg9 transport by differential interactions with the ER tether and the Beclin1 complex

ER-Golgi membrane transport and autophagy are intersecting trafficking pathways that are tightly regulated and crucial for homeostasis, development and diseases. Here, we identify UVRAG, a Beclin1-binding autophagic factor, as a PI(3)P-binding protein that depends on PI(3)P for its ER localization....

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Detalles Bibliográficos
Autores principales: He, Shanshan, Ni, Duojiao, Ma, Binyun, Lee, Joo-Hyung, Zhang, Tian, Ghozalli, Irene, Pirooz, Sara Dolatshahi, Zhao, Zhen, Bharatham, Nagakumar, Li, Baihong, Oh, Soohwan, Lee, Wen-Hwa, Takahashi, Yoshinori, Wang, Hong-Gang, Minassian, Arlet, Feng, Pinghui, Deretic, Vojo, Pepperkok, Rainer, Tagaya, Mitsuo, Yoon, Ho Sup, Liang, Chengyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805255/
https://www.ncbi.nlm.nih.gov/pubmed/24056303
http://dx.doi.org/10.1038/ncb2848

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