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BCL::EMAS — Enantioselective Molecular Asymmetry Descriptor for 3D-QSAR
Stereochemistry is an important determinant of a molecule’s biological activity. Stereoisomers can have different degrees of efficacy or even opposing effects when interacting with a target protein. Stereochemistry is a molecular property difficult to represent in 2D-QSAR as it is an inherently thre...
Autores principales: | Sliwoski, Gregory, Lowe, Edward W., Butkiewicz, Mariusz, Meiler, Jens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805266/ https://www.ncbi.nlm.nih.gov/pubmed/22907158 http://dx.doi.org/10.3390/molecules17089971 |
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