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Two Replication Fork Maintenance Pathways Fuse Inverted Repeats to Rearrange Chromosomes
Replication fork (RF) maintenance pathways preserve chromosomes, but their faulty application at nonallelic repeats could generate rearrangements causing cancer, genomic disorders and speciation(1-3). Potential causal mechanisms are homologous recombination (HR) and error-free postreplication repair...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805358/ https://www.ncbi.nlm.nih.gov/pubmed/24013173 http://dx.doi.org/10.1038/nature12500 |