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Two Replication Fork Maintenance Pathways Fuse Inverted Repeats to Rearrange Chromosomes

Replication fork (RF) maintenance pathways preserve chromosomes, but their faulty application at nonallelic repeats could generate rearrangements causing cancer, genomic disorders and speciation(1-3). Potential causal mechanisms are homologous recombination (HR) and error-free postreplication repair...

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Detalles Bibliográficos
Autores principales: Hu, Lingchuan, Kim, Tae Moon, Son, Mi Young, Kim, Sung-A, Holland, Cory L., Tateishi, Satoshi, Kim, Dong Hyun, Yew, P. Renee, Montagna, Cristina, Dumitrache, Lavinia C., Hasty, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805358/
https://www.ncbi.nlm.nih.gov/pubmed/24013173
http://dx.doi.org/10.1038/nature12500