A Transcriptional Signature for Active TB: Have We Found the Needle in the Haystack?

Adithya Cattamanchi and colleagues reflect on recent research by Michael Levin and coworkers into the use of whole blood mRNA expression signatures to detect tuberculosis. The authors highlight challenges faced in getting this promising technology into clinics in low-resource settings. Please see la...

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Detalles Bibliográficos
Autores principales: Cattamanchi, Adithya, Walter, Nicholas D., Metcalfe, John Z., Davis, J. Lucian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805486/
https://www.ncbi.nlm.nih.gov/pubmed/24167454
http://dx.doi.org/10.1371/journal.pmed.1001539
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author Cattamanchi, Adithya
Walter, Nicholas D.
Metcalfe, John Z.
Davis, J. Lucian
author_facet Cattamanchi, Adithya
Walter, Nicholas D.
Metcalfe, John Z.
Davis, J. Lucian
author_sort Cattamanchi, Adithya
collection PubMed
description Adithya Cattamanchi and colleagues reflect on recent research by Michael Levin and coworkers into the use of whole blood mRNA expression signatures to detect tuberculosis. The authors highlight challenges faced in getting this promising technology into clinics in low-resource settings. Please see later in the article for the Editors' Summary
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spelling pubmed-38054862013-10-28 A Transcriptional Signature for Active TB: Have We Found the Needle in the Haystack? Cattamanchi, Adithya Walter, Nicholas D. Metcalfe, John Z. Davis, J. Lucian PLoS Med Perspective Adithya Cattamanchi and colleagues reflect on recent research by Michael Levin and coworkers into the use of whole blood mRNA expression signatures to detect tuberculosis. The authors highlight challenges faced in getting this promising technology into clinics in low-resource settings. Please see later in the article for the Editors' Summary Public Library of Science 2013-10-22 /pmc/articles/PMC3805486/ /pubmed/24167454 http://dx.doi.org/10.1371/journal.pmed.1001539 Text en © 2013 Cattamanchi et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Perspective
Cattamanchi, Adithya
Walter, Nicholas D.
Metcalfe, John Z.
Davis, J. Lucian
A Transcriptional Signature for Active TB: Have We Found the Needle in the Haystack?
title A Transcriptional Signature for Active TB: Have We Found the Needle in the Haystack?
title_full A Transcriptional Signature for Active TB: Have We Found the Needle in the Haystack?
title_fullStr A Transcriptional Signature for Active TB: Have We Found the Needle in the Haystack?
title_full_unstemmed A Transcriptional Signature for Active TB: Have We Found the Needle in the Haystack?
title_short A Transcriptional Signature for Active TB: Have We Found the Needle in the Haystack?
title_sort transcriptional signature for active tb: have we found the needle in the haystack?
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805486/
https://www.ncbi.nlm.nih.gov/pubmed/24167454
http://dx.doi.org/10.1371/journal.pmed.1001539
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