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Bupleurum Polysaccharides Attenuates Lipopolysaccharide-Induced Inflammation via Modulating Toll-Like Receptor 4 Signaling

BACKGROUND: Bupleurum polysaccharides (BPs), isolated from Bupleurum smithii var. parvifolium, possesses immunomodulatory activity, particularly on inflammation. Bacterial endotoxin lipopolysaccharide (LPS) triggers innate immune responses through Toll-like receptor 4 (TLR4) on host cell membrane. T...

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Detalles Bibliográficos
Autores principales: Wu, Jian, Zhang, Yun-Yi, Guo, Li, Li, Hong, Chen, Dao-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805517/
https://www.ncbi.nlm.nih.gov/pubmed/24167596
http://dx.doi.org/10.1371/journal.pone.0078051