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Bupleurum Polysaccharides Attenuates Lipopolysaccharide-Induced Inflammation via Modulating Toll-Like Receptor 4 Signaling
BACKGROUND: Bupleurum polysaccharides (BPs), isolated from Bupleurum smithii var. parvifolium, possesses immunomodulatory activity, particularly on inflammation. Bacterial endotoxin lipopolysaccharide (LPS) triggers innate immune responses through Toll-like receptor 4 (TLR4) on host cell membrane. T...
Autores principales: | Wu, Jian, Zhang, Yun-Yi, Guo, Li, Li, Hong, Chen, Dao-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805517/ https://www.ncbi.nlm.nih.gov/pubmed/24167596 http://dx.doi.org/10.1371/journal.pone.0078051 |
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