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Differential Effects of Genistein on Prostate Cancer Cells Depend on Mutational Status of the Androgen Receptor

Blocking the androgen receptor (AR) activity is the main goal of therapies for advanced prostate cancer (PCa). However, relapse with a more aggressive, hormone refractory PCa arises, which harbors restored AR activity. One mechanism of such reactivation occurs through acquisition of AR mutations tha...

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Detalles Bibliográficos
Autores principales:	Mahmoud, Abeer M., Zhu, Tian, Parray, Aijaz, Siddique, Hifzur R., Yang, Wancai, Saleem, Mohammad, Bosland, Maarten C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805529/ https://www.ncbi.nlm.nih.gov/pubmed/24167630 http://dx.doi.org/10.1371/journal.pone.0078479

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