Transient Inhibition of FGFR2b-Ligands Signaling Leads to Irreversible Loss of Cellular β-Catenin Organization and Signaling in AER during Mouse Limb Development

The vertebrate limbs develop through coordinated series of inductive, growth and patterning events. Fibroblast Growth Factor receptor 2b (FGFR2b) signaling controls the induction of the Apical Ectodermal Ridge (AER) but its putative roles in limb outgrowth and patterning, as well as in AER morpholog...

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Detalles Bibliográficos
Autores principales: Danopoulos, Soula, Parsa, Sara, Al Alam, Denise, Tabatabai, Reza, Baptista, Sheryl, Tiozzo, Caterina, Carraro, Gianni, Wheeler, Matthew, Barreto, Guillermo, Braun, Thomas, Li, Xiaokun, Hajihosseini, Mohammad K., Bellusci, Saverio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805551/
https://www.ncbi.nlm.nih.gov/pubmed/24167544
http://dx.doi.org/10.1371/journal.pone.0076248

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