LRRK2 Affects Vesicle Trafficking, Neurotransmitter Extracellular Level and Membrane Receptor Localization

The leucine-rich repeat kinase 2 (LRRK2) gene was found to play a role in the pathogenesis of both familial and sporadic Parkinson’s disease (PD). LRRK2 encodes a large multi-domain protein that is expressed in different tissues. To date, the physiological and pathological functions of LRRK2 are not...

Descripción completa

Detalles Bibliográficos
Autores principales: Migheli, Rossana, Del Giudice, Maria Grazia, Spissu, Ylenia, Sanna, Giovanna, Xiong, Yulan, Dawson, Ted M., Dawson, Valina L., Galioto, Manuela, Rocchitta, Gaia, Biosa, Alice, Serra, Pier Andrea, Carri, Maria Teresa, Crosio, Claudia, Iaccarino, Ciro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805556/
https://www.ncbi.nlm.nih.gov/pubmed/24167564
http://dx.doi.org/10.1371/journal.pone.0077198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805556/
https://www.ncbi.nlm.nih.gov/pubmed/24167564
http://dx.doi.org/10.1371/journal.pone.0077198

Ejemplares similares