Cargando…

Functional Analysis of Deep Intronic SNP rs13438494 in Intron 24 of PCLO Gene

The single nucleotide polymorphism (SNP) rs13438494 in intron 24 of PCLO was significantly associated with bipolar disorder in a meta-analysis of genome-wide association studies. In this study, we performed functional minigene analysis and bioinformatics prediction of splicing regulatory sequences t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Seo, Seunghee, Takayama, Kanako, Uno, Kyosuke, Ohi, Kazutaka, Hashimoto, Ryota, Nishizawa, Daisuke, Ikeda, Kazutaka, Ozaki, Norio, Nabeshima, Toshitaka, Miyamoto, Yoshiaki, Nitta, Atsumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805565/ https://www.ncbi.nlm.nih.gov/pubmed/24167553 http://dx.doi.org/10.1371/journal.pone.0076960

Ejemplares similares

PM314. Knockdown Piccolo suppressed Methamphetamine-induced behavioral changes and dopamine release in the nucleus accumbens of mice
por: Ge, Bin, et al.
Publicado: (2016)

PM487. Presynaptic protein Piccolo knockdown in the prefrontal cortex induces cognitive and emotional impairment in mice.
por: Miyamoto, Yoshiaki, et al.
Publicado: (2016)

PS122. Overexpression of N-acetyltransferase Shati/Nat8l in the dorsal striatum induces depression-like behaviors in mice.
por: Sodeyama, Kengo, et al.
Publicado: (2016)

Behavioral impairment in SHATI/NAT8L knockout mice via dysfunction of myelination development
por: Sumi, Kazuyuki, et al.
Publicado: (2017)

Identification of an intronic enhancer regulating RANKL expression in osteocytic cells
por: Yan, Minglu, et al.
Publicado: (2023)

Intronization, de-intronization and intron sliding are rare in Cryptococcus
por: Roy, Scott W
Publicado: (2009)

Methamphetamine induces Shati/Nat8L expression in the mouse nucleus accumbens via CREB- and dopamine D1 receptor-dependent mechanism
por: Uno, Kyosuke, et al.
Publicado: (2017)

Introns: The Functional Benefits of Introns in Genomes
por: Jo, Bong-Seok, et al.
Publicado: (2015)

Characterization of PCLO Gene in Amazonian Native American Populations
por: Cohen-Paes, Amanda de Nazaré, et al.
Publicado: (2022)

Decreased DNA Methylation in the Shati/Nat8l Promoter in Both Patients with Schizophrenia and a Methamphetamine-Induced Murine Model of Schizophrenia-Like Phenotype
por: Uno, Kyosuke, et al.
Publicado: (2016)

At the origin of spliceosomal introns: Is multiplication of introner-like elements the main mechanism of intron gain in fungi?
por: Collemare, Jérôme, et al.
Publicado: (2013)

The Complex Intron Landscape and Massive Intron Invasion in a Picoeukaryote Provides Insights into Intron Evolution
por: Verhelst, Bram, et al.
Publicado: (2013)

Phase distribution of spliceosomal introns: implications for intron origin
por: Nguyen, Hung D, et al.
Publicado: (2006)

The origin of introns and their role in eukaryogenesis: a compromise solution to the introns-early versus introns-late debate?
por: Koonin, Eugene V
Publicado: (2006)

The Function of Introns
por: Chorev, Michal, et al.
Publicado: (2012)

Introns in Cryptococcus
por: Janbon, Guilhem
Publicado: (2018)

PM315. Pseudoginsenoside-F11 inhibits methamphetamine dependence by regulating GABAergic and opioidergic neuronal system in the nucleus accumbens of mice
por: Fu, Kequan, et al.
Publicado: (2016)

Intron Evolution: Testing Hypotheses of Intron Evolution Using the Phylogenomics of Tetraspanins
por: Garcia-España, Antonio, et al.
Publicado: (2009)

Evolutionary history of teleost intron-containing and intron-less rhodopsin genes
por: Fujiyabu, Chihiro, et al.
Publicado: (2019)

Development of EST Intron-Targeting SNP Markers for Panax ginseng and Their Application to Cultivar Authentication
por: Wang, Hongtao, et al.
Publicado: (2016)

An intron SNP rs2069837 in IL-6 is associated with osteonecrosis of the femoral head development
por: Wang, Ruisong, et al.
Publicado: (2022)

Overexpression of transmembrane protein 168 in the mouse nucleus accumbens induces anxiety and sensorimotor gating deficit
por: Fu, Kequan, et al.
Publicado: (2017)

On the Estimation of Intron Evolution
por: Csűrös, Miklós
Publicado: (2006)

Intron Evolution in Saccharomycetaceae
por: Hooks, Katarzyna B., et al.
Publicado: (2014)

InTRONs in Biotech
por: Skoko, Natasa, et al.
Publicado: (2011)

Imaging Intron Evolution
por: Panaro, Maria Antonietta, et al.
Publicado: (2022)

Group II intron–ribosome association protects intron RNA from degradation
por: Contreras, Lydia M., et al.
Publicado: (2013)

Novel Introner-Like Elements in fungi Are Involved in Parallel Gains of Spliceosomal Introns
por: Collemare, Jérôme, et al.
Publicado: (2015)

Detained introns are a novel, widespread class of post-transcriptionally spliced introns
por: Boutz, Paul L., et al.
Publicado: (2015)

PlantIntronDB: a database for plant introns that host functional elements
por: Wang, Weiping, et al.
Publicado: (2023)

The leader intron of AtMHX can elicit, in the absence of splicing, low-level intron-mediated enhancement that depends on the internal intron sequence
por: Akua, Tsofit, et al.
Publicado: (2010)

Minor intron splicing revisited: identification of new minor intron-containing genes and tissue-dependent retention and alternative splicing of minor introns
por: Olthof, Anouk M., et al.
Publicado: (2019)

Involvement of the accumbal osteopontin-interacting transmembrane protein 168 in methamphetamine-induced place preference and hyperlocomotion in mice
por: Fu, Kequan, et al.
Publicado: (2017)

PCLO rs2522833 impacts HPA system activity in healthy young adults
por: Kuehner, C, et al.
Publicado: (2011)

Testing the IMEter on rice introns and other aspects of intron-mediated enhancement of gene expression
por: Morello, Laura, et al.
Publicado: (2011)

Imprecise intron losses are less frequent than precise intron losses but are not rare in plants
por: Ma, Ming-Yue, et al.
Publicado: (2015)

Computational identification of functional introns: high positional conservation of introns that harbor RNA genes
por: Chorev, Michal, et al.
Publicado: (2013)

Stable intronic sequence RNAs (sisRNAs) are selected regions in introns with distinct properties
por: Jin, Jing, et al.
Publicado: (2020)

Analysis on the interactions between the first introns and other introns in mitochondrial ribosomal protein genes
por: Li, Ruifang, et al.
Publicado: (2022)

Intron mis-splicing: no alternative?
por: Roy, Scott William, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_vc063jdi24nmvj6e58ost85arv