Improved Glucose Control and Reduced Body Weight in Rodents with Dual Mechanism of Action Peptide Hybrids

Combination therapy is being increasingly used as a treatment paradigm for metabolic diseases such as diabetes and obesity. In the peptide therapeutics realm, recent work has highlighted the therapeutic potential of chimeric peptides that act on two distinct receptors, thereby harnessing parallel co...

Descripción completa

Detalles Bibliográficos
Autores principales: Trevaskis, James L., Mack, Christine M., Sun, Chengzao, Soares, Christopher J., D’Souza, Lawrence J., Levy, Odile E., Lewis, Diane Y., Jodka, Carolyn M., Tatarkiewicz, Krystyna, Gedulin, Bronislava, Gupta, Swati, Wittmer, Carrie, Hanley, Michael, Forood, Bruce, Parkes, David G., Ghosh, Soumitra S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805588/
https://www.ncbi.nlm.nih.gov/pubmed/24167604
http://dx.doi.org/10.1371/journal.pone.0078154

Ejemplares similares

Ejemplares similares