Thiopental Inhibits Global Protein Synthesis by Repression of Eukaryotic Elongation Factor 2 and Protects from Hypoxic Neuronal Cell Death

Ischemic and traumatic brain injury is associated with increased risk for death and disability. The inhibition of penumbral tissue damage has been recognized as a target for therapeutic intervention, because cellular injury evolves progressively upon ATP-depletion and loss of ion homeostasis. In pat...

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Detalles Bibliográficos
Autores principales: Schwer, Christian I., Lehane, Cornelius, Guelzow, Timo, Zenker, Simone, Strosing, Karl M., Spassov, Sashko, Erxleben, Anika, Heimrich, Bernd, Buerkle, Hartmut, Humar, Matjaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805597/
https://www.ncbi.nlm.nih.gov/pubmed/24167567
http://dx.doi.org/10.1371/journal.pone.0077258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805597/
https://www.ncbi.nlm.nih.gov/pubmed/24167567
http://dx.doi.org/10.1371/journal.pone.0077258

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