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Microsatellite instability in hematological malignancies: Hypermutation vs. immune control—who is challenging who?
The genome of colorectal carcinomas displaying pronounced microsatellite instability codes for an extraordinarily high number of mutated proteins that elicit tumor-specific cellular immune responses. We have recently demonstrated that leukemic cells are also vulnerable to T cells specific for tumor-...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805632/ https://www.ncbi.nlm.nih.gov/pubmed/24167765 http://dx.doi.org/10.4161/onci.25419 |