Airway Administration of Vascular Endothelial Growth Factor siRNAs Induces Transient Airspace Enlargement in Mice

Purpose: Reduction in the level of vascular endothelial growth factor (VEGF) has been implicated in the pathogenesis of pulmonary emphysema. To this end, pharmacological VEGF receptor blockade, and the Cre-lox system models have been utilized to study the effects of VEGF depletion in the lung. These...

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Detalles Bibliográficos
Autores principales: Takahashi, Yusuke, Izumi, Yotaro, Kohno, Mitsutomo, Ikeda, Eiji, Nomori, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805924/
https://www.ncbi.nlm.nih.gov/pubmed/24155658
http://dx.doi.org/10.7150/ijms.7114

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