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DNA Methylation Profiling Revealed Promoter Hypermethylation-induced Silencing of p16, DDAH2 and DUSP1 in Primary Oral Squamous Cell Carcinoma

Background: Hypermethylation in promoter regions of genes might lead to altered gene functions and result in malignant cellular transformation. Thus, biomarker identification for hypermethylated genes would be very useful for early diagnosis, prognosis, and therapeutic treatment of oral squamous cel...

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Detalles Bibliográficos
Autores principales: Khor, Goot Heah, Froemming, Gabriele Ruth Anisah, Zain, Rosnah Binti, Abraham, Mannil Thomas, Omar, Effat, Tan, Su Keng, Tan, Aik Choon, Vincent-Chong, Vui King, Thong, Kwai Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805925/
https://www.ncbi.nlm.nih.gov/pubmed/24155659
http://dx.doi.org/10.7150/ijms.6884

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