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The Control of the Specificity of CD4 T Cell Responses: Thresholds, Breakpoints, and Ceilings
It has been known for over 25 years that CD4 T cell responses are restricted to a finite number of peptide epitopes within pathogens or protein vaccines. These selected peptide epitopes are termed “immunodominant.” Other peptides within the antigen that can bind to host MHC molecules and recruit CD4...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805957/ https://www.ncbi.nlm.nih.gov/pubmed/24167504 http://dx.doi.org/10.3389/fimmu.2013.00340 |