Exploring the Nicotinic Acetylcholine Receptor-associated Proteome with iTRAQ and Transgenic Mice

Neuronal nicotinic acetylcholine receptors (nAChRs) containing α4 and β2 subunits are the principal receptors in the mammalian central nervous system that bind nicotine with high affinity. These nAChRs are involved in nicotine dependence, mood disorders, neurodegeneration and neuroprotection. Howeve...

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Detalles Bibliográficos
Autores principales: McClure-Begley, Tristan D., Stone, Kathy L., Marks, Michael J., Grady, Sharon R., Colangelo, Christopher M., Lindstrom, Jon M., Picciotto, Marina R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806329/
https://www.ncbi.nlm.nih.gov/pubmed/23891776
http://dx.doi.org/10.1016/j.gpb.2013.05.005

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