Hydrodynamic immunization leads to poor CD8 T-cell expansion, low frequency of memory CTLs and ineffective antiviral protection

Hepatotropic pathogens, such as hepatitis B (HBV) and hepatitis C (HCV), often escape cellular immune clearance resulting in chronic infection. As HBV and HCV infections are the most common causes of hepatocellular carcinoma (HCC), prevention of these infections is believed to be key to the preventi...

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Detalles Bibliográficos
Autores principales: Obeng-Adjei, N, Choo, D K, Weiner, D B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806376/
https://www.ncbi.nlm.nih.gov/pubmed/23969886
http://dx.doi.org/10.1038/cgt.2013.52

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806376/
https://www.ncbi.nlm.nih.gov/pubmed/23969886
http://dx.doi.org/10.1038/cgt.2013.52

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