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Detection of low frequency FGFR3 mutations in the urine of bladder cancer patients using next-generation deep sequencing
Biological fluid-based noninvasive biomarker assays for monitoring and diagnosing disease are clinically powerful. A major technical hurdle for developing these assays is the requirement of high analytical sensitivity so that biomarkers present at very low levels can be consistently detected. In the...
Autores principales: | Millholland, John M, Li, Shuqiang, Fernandez, Cecilia A, Shuber, Anthony P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806441/ https://www.ncbi.nlm.nih.gov/pubmed/24199178 http://dx.doi.org/10.2147/RRU.S32736 |
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