The Marine Natural Product Manzamine A Targets Vacuolar ATPases and Inhibits Autophagy in Pancreatic Cancer Cells

Manzamine A, a member of the manzamine alkaloids, was originally isolated from marine sponges of the genus Haliclona. It was recently shown to have activity against pancreatic cancer cells, but the precise mechanism of action remained unclear. To further our understanding of the mechanism of action...

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Detalles Bibliográficos
Autores principales: Kallifatidis, Georgios, Hoepfner, Dominic, Jaeg, Tiphaine, Guzmán, Esther A., Wright, Amy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806460/
https://www.ncbi.nlm.nih.gov/pubmed/24048269
http://dx.doi.org/10.3390/md11093500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806460/
https://www.ncbi.nlm.nih.gov/pubmed/24048269
http://dx.doi.org/10.3390/md11093500

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