Optimal Cleavage and Oxidative Folding of α-Conotoxin TxIB as a Therapeutic Candidate Peptide

Alpha6beta2 nicotinic acetylcholine receptors (nAChRs) are potential therapeutic targets for the treatment of several neuropsychiatric diseases, including addiction and Parkinson’s disease. Alpha-conotoxin (α-CTx) TxIB is a uniquely selective ligand, which blocks α6/α3β2β3 nAChRs only, but does not...

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Detalles Bibliográficos
Autores principales: Wu, Xiaosa, Wu, Yong, Zhu, Furong, Yang, Qiuyuan, Wu, Qianqian, Zhangsun, Dongting, Luo, Sulan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806463/
https://www.ncbi.nlm.nih.gov/pubmed/24048271
http://dx.doi.org/10.3390/md11093537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806463/
https://www.ncbi.nlm.nih.gov/pubmed/24048271
http://dx.doi.org/10.3390/md11093537

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