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The Cement Prosthesis-Like Spacer: An Intermediate Halt on the Road to Healing

Background. Periprosthetic infections remain a devastating problem in the field of joint arthroplasty. In the following study, the results of a two-stage treatment protocol for chronic periprosthetic infections using an intraoperatively molded cement prosthesis-like spacer (CPLS) are presented. Meth...

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Autores principales: Ahmad, Sufian S., Huber, Kim, Evangelopoulos, Dimitrios S., Kleer, Barbara, Kohlhof, Hendrik, Schär, Michael, Eggli, Stefan, Kohl, Sandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806478/
https://www.ncbi.nlm.nih.gov/pubmed/24198728
http://dx.doi.org/10.1155/2013/763434
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author Ahmad, Sufian S.
Huber, Kim
Evangelopoulos, Dimitrios S.
Kleer, Barbara
Kohlhof, Hendrik
Schär, Michael
Eggli, Stefan
Kohl, Sandro
author_facet Ahmad, Sufian S.
Huber, Kim
Evangelopoulos, Dimitrios S.
Kleer, Barbara
Kohlhof, Hendrik
Schär, Michael
Eggli, Stefan
Kohl, Sandro
author_sort Ahmad, Sufian S.
collection PubMed
description Background. Periprosthetic infections remain a devastating problem in the field of joint arthroplasty. In the following study, the results of a two-stage treatment protocol for chronic periprosthetic infections using an intraoperatively molded cement prosthesis-like spacer (CPLS) are presented. Methods. Seventy-five patients with chronically infected knee prosthesis received a two-stage revision procedure with the newly developed CPLS between June 2006 and June 2011. Based on the microorganism involved, patients were grouped into either easy to treat (ETT) or difficult to treat (DTT) and treated accordingly. Range of motion (ROM) and the knee society score (KSS) were utilized for functional assessment. Results. Mean duration of the CPLS implant in the DTT group was 3.6 months (range 3–5 months) and in the ETT group 1.3 months (range 0.7–2.5 months). Reinfection rates of the final prosthesis were 9.6% in the ETT and 8.3% in the DTT group with no significant difference between both groups regarding ROM or KSS (P = 0.87, 0.64, resp.). Conclusion. The results show that ETT patients do not necessitate the same treatment protocol as DTT patients to achieve the same goal, emphasizing the need to differentiate between therapeutic regimes. We also highlight the feasibility of CLPS in two-stage protocols.
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spelling pubmed-38064782013-11-06 The Cement Prosthesis-Like Spacer: An Intermediate Halt on the Road to Healing Ahmad, Sufian S. Huber, Kim Evangelopoulos, Dimitrios S. Kleer, Barbara Kohlhof, Hendrik Schär, Michael Eggli, Stefan Kohl, Sandro ScientificWorldJournal Clinical Study Background. Periprosthetic infections remain a devastating problem in the field of joint arthroplasty. In the following study, the results of a two-stage treatment protocol for chronic periprosthetic infections using an intraoperatively molded cement prosthesis-like spacer (CPLS) are presented. Methods. Seventy-five patients with chronically infected knee prosthesis received a two-stage revision procedure with the newly developed CPLS between June 2006 and June 2011. Based on the microorganism involved, patients were grouped into either easy to treat (ETT) or difficult to treat (DTT) and treated accordingly. Range of motion (ROM) and the knee society score (KSS) were utilized for functional assessment. Results. Mean duration of the CPLS implant in the DTT group was 3.6 months (range 3–5 months) and in the ETT group 1.3 months (range 0.7–2.5 months). Reinfection rates of the final prosthesis were 9.6% in the ETT and 8.3% in the DTT group with no significant difference between both groups regarding ROM or KSS (P = 0.87, 0.64, resp.). Conclusion. The results show that ETT patients do not necessitate the same treatment protocol as DTT patients to achieve the same goal, emphasizing the need to differentiate between therapeutic regimes. We also highlight the feasibility of CLPS in two-stage protocols. Hindawi Publishing Corporation 2013-09-30 /pmc/articles/PMC3806478/ /pubmed/24198728 http://dx.doi.org/10.1155/2013/763434 Text en Copyright © 2013 Sufian S. Ahmad et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Ahmad, Sufian S.
Huber, Kim
Evangelopoulos, Dimitrios S.
Kleer, Barbara
Kohlhof, Hendrik
Schär, Michael
Eggli, Stefan
Kohl, Sandro
The Cement Prosthesis-Like Spacer: An Intermediate Halt on the Road to Healing
title The Cement Prosthesis-Like Spacer: An Intermediate Halt on the Road to Healing
title_full The Cement Prosthesis-Like Spacer: An Intermediate Halt on the Road to Healing
title_fullStr The Cement Prosthesis-Like Spacer: An Intermediate Halt on the Road to Healing
title_full_unstemmed The Cement Prosthesis-Like Spacer: An Intermediate Halt on the Road to Healing
title_short The Cement Prosthesis-Like Spacer: An Intermediate Halt on the Road to Healing
title_sort cement prosthesis-like spacer: an intermediate halt on the road to healing
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806478/
https://www.ncbi.nlm.nih.gov/pubmed/24198728
http://dx.doi.org/10.1155/2013/763434
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