Rhein Protects Pancreatic β-Cells From Dynamin-Related Protein-1–Mediated Mitochondrial Fission and Cell Apoptosis Under Hyperglycemia

Rhein, an anthraquinone compound isolated from rhubarb, has been shown to improve glucose metabolism disorders in diabetic mice. The mechanism underlying the protective effect of rhein, however, remains unknown. Here, we demonstrate that rhein can protect the pancreatic β-cells against hyperglycemia...

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Detalles Bibliográficos
Autores principales: Liu, Jing, Chen, Zhaohong, Zhang, Yujing, Zhang, Mingchao, Zhu, Xiaodong, Fan, Yun, Shi, Shaolin, Zen, Ke, Liu, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806614/
https://www.ncbi.nlm.nih.gov/pubmed/23919963
http://dx.doi.org/10.2337/db13-0251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806614/
https://www.ncbi.nlm.nih.gov/pubmed/23919963
http://dx.doi.org/10.2337/db13-0251

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