Hypersensitivity to Etoposide in Case of Metastatic Gestational Choriocarcinoma

Etoposide is commonly used in the treatment of a variety of neoplasms. Hypersensitivity reactions to etoposide are infrequently reported and include hypotension, hypertension, flushing, diaphoresis, chest discomfort, dyspnea, bronchospasm and loss of consciousness. We report the case of a 39-year-ol...

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Autores principales: Lazović, Biljana, Milenković, Vera, Delić, Marina, Mazić, Sanja, Jeremic, Katarina, Hrgović, Zlatko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2013
Materias:
Published online: September, 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806672/
https://www.ncbi.nlm.nih.gov/pubmed/24163666
http://dx.doi.org/10.1159/000353627
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author Lazović, Biljana
Milenković, Vera
Delić, Marina
Mazić, Sanja
Jeremic, Katarina
Hrgović, Zlatko
author_facet Lazović, Biljana
Milenković, Vera
Delić, Marina
Mazić, Sanja
Jeremic, Katarina
Hrgović, Zlatko
author_sort Lazović, Biljana
collection PubMed
description Etoposide is commonly used in the treatment of a variety of neoplasms. Hypersensitivity reactions to etoposide are infrequently reported and include hypotension, hypertension, flushing, diaphoresis, chest discomfort, dyspnea, bronchospasm and loss of consciousness. We report the case of a 39-year-old woman who experienced acute bronchospasm, tachycardia, hypoxia and hypotension. The symptoms resolved within an hour after administration of intravenous fluids, methylprednisolone, diphenhydramine and oxygen. Subsequently, the patient was given etoposide phosphate without incident.
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spelling pubmed-38066722013-10-25 Hypersensitivity to Etoposide in Case of Metastatic Gestational Choriocarcinoma Lazović, Biljana Milenković, Vera Delić, Marina Mazić, Sanja Jeremic, Katarina Hrgović, Zlatko Case Rep Oncol Published online: September, 2013 Etoposide is commonly used in the treatment of a variety of neoplasms. Hypersensitivity reactions to etoposide are infrequently reported and include hypotension, hypertension, flushing, diaphoresis, chest discomfort, dyspnea, bronchospasm and loss of consciousness. We report the case of a 39-year-old woman who experienced acute bronchospasm, tachycardia, hypoxia and hypotension. The symptoms resolved within an hour after administration of intravenous fluids, methylprednisolone, diphenhydramine and oxygen. Subsequently, the patient was given etoposide phosphate without incident. S. Karger AG 2013-09-26 /pmc/articles/PMC3806672/ /pubmed/24163666 http://dx.doi.org/10.1159/000353627 Text en Copyright © 2013 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published online: September, 2013
Lazović, Biljana
Milenković, Vera
Delić, Marina
Mazić, Sanja
Jeremic, Katarina
Hrgović, Zlatko
Hypersensitivity to Etoposide in Case of Metastatic Gestational Choriocarcinoma
title Hypersensitivity to Etoposide in Case of Metastatic Gestational Choriocarcinoma
title_full Hypersensitivity to Etoposide in Case of Metastatic Gestational Choriocarcinoma
title_fullStr Hypersensitivity to Etoposide in Case of Metastatic Gestational Choriocarcinoma
title_full_unstemmed Hypersensitivity to Etoposide in Case of Metastatic Gestational Choriocarcinoma
title_short Hypersensitivity to Etoposide in Case of Metastatic Gestational Choriocarcinoma
title_sort hypersensitivity to etoposide in case of metastatic gestational choriocarcinoma
topic Published online: September, 2013
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806672/
https://www.ncbi.nlm.nih.gov/pubmed/24163666
http://dx.doi.org/10.1159/000353627
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