Inference of Gene-Phenotype Associations via Protein-Protein Interaction and Orthology

One of the fundamental goals of genetics is to understand gene functions and their associated phenotypes. To achieve this goal, in this study we developed a computational algorithm that uses orthology and protein-protein interaction information to infer gene-phenotype associations for multiple speci...

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Detalles Bibliográficos
Autores principales: Wang, Panwen, Lai, Wing-Fu, Li, Mulin Jun, Xu, Feng, Yalamanchili, Hari Krishna, Lovell-Badge, Robin, Wang, Junwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806783/
https://www.ncbi.nlm.nih.gov/pubmed/24194887
http://dx.doi.org/10.1371/journal.pone.0077478

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