Proteolysis during Tumor Cell Extravasation In Vitro: Metalloproteinase Involvement across Tumor Cell Types

To test if proteolysis is involved in tumor cell extravasation, we developed an in vitro model where tumor cells cross an endothelial monolayer cultured on a basement membrane. Using this model we classified the ability of the cells to transmigrate through the endothelial cell barrier onto the under...

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Detalles Bibliográficos
Autores principales: Voura, Evelyn B., English, Jane L., Yu, Hoi-Ying E., Ho, Andrew T., Subarsky, Patrick, Hill, Richard P., Hojilla, Carlo V., Khokha, Rama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806793/
https://www.ncbi.nlm.nih.gov/pubmed/24194929
http://dx.doi.org/10.1371/journal.pone.0078413

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