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Epstein-Barr Virus_Encoded LMP1 Upregulates MicroRNA-21 to Promote the Resistance of Nasopharyngeal Carcinoma Cells to Cisplatin-Induced Apoptosis by Suppressing PDCD4 and Fas-L

Approximately 30% of patients with Epstein-Barr virus (EBV)-positive advanced nasopharyngeal carcinoma (NPC) display chemoresistance to cisplatin-based regimens, but the underlying mechanisms are unclear. The Epstein-Barr virus (EBV)-encoded latent membrane protein 1 (LMP1), a functional homologue o...

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Detalles Bibliográficos
Autores principales: Yang, Guang-Da, Huang, Tie-Jun, Peng, Li-Xia, Yang, Chang-Fu, Liu, Ran-Yi, Huang, Hong-Bing, Chu, Qiao-Qiao, Yang, Hong-Jie, Huang, Jia-Ling, Zhu, Zhen-Yu, Qian, Chao-Nan, Huang, Bi-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806812/
https://www.ncbi.nlm.nih.gov/pubmed/24194922
http://dx.doi.org/10.1371/journal.pone.0078355

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