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MicroRNA-17, 20a Regulates the Proangiogenic Function of Tumor-Associated Macrophages via Targeting Hypoxia-Inducible Factor 2α

Tumor-associated macrophages (TAMs) constitute a major component of the leukocyte infiltrate of most solid tumors, and they usually exhibit a proangiogenic phenotype which facilitates tumor growth in most circumstances. However, the precise mechanisms regulating the proangiogenic properties of TAMs...

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Detalles Bibliográficos
Autores principales: Xu, Zhenqun, Zhao, Lan, Zhu, Ling-Yan, He, Min, Zheng, Limin, Wu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806827/
https://www.ncbi.nlm.nih.gov/pubmed/24194900
http://dx.doi.org/10.1371/journal.pone.0077890