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Cholera Toxin Enhances Vaccine-Induced Protection against Mycobacterium Tuberculosis Challenge in Mice

Interleukin (IL)-17 is emerging as an important cytokine in vaccine-induced protection against tuberculosis disease in animal models. Here we show that compared to parenteral delivery, BCG delivered mucosally enhances cytokine production, including interferon gamma and IL-17, in the lungs. Furthermo...

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Detalles Bibliográficos
Autores principales: Griffiths, Kristin L., Stylianou, Elena, Poyntz, Hazel C., Betts, Gareth J., Fletcher, Helen A., McShane, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806838/
https://www.ncbi.nlm.nih.gov/pubmed/24194918
http://dx.doi.org/10.1371/journal.pone.0078312