Brd2 Inhibits Adipogenesis via the ERK1/2 Signaling Pathway in 3T3-L1 Adipocytes

Bromodomain-containing protein 2 (Brd2) is a nuclear serine/threonine kinase involved in transcriptional regulation. In 3T3-L1 adipocytes, Brd2 normally co-represses PPARγ (peroxisome proliferator-activated receptor gamma) and inhibits adipogenesis. Here, we show that Brd2 over-expression in preadip...

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Detalles Bibliográficos
Autores principales: Zang, Kun, Wang, Jingyu, Dong, Miaofang, Sun, Ruixin, Wang, Yuxiong, Huang, Yinong, Liu, Xiaoxia, Li, Yimin, Wang, Fangnian, Yu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806839/
https://www.ncbi.nlm.nih.gov/pubmed/24194944
http://dx.doi.org/10.1371/journal.pone.0078536

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