Cargando…

DNA-Dependent Protein Kinase Is a Context Dependent Regulator of Lmx1a and Midbrain Specification

The identification of small molecules capable of directing pluripotent cell differentiation towards specific lineages is highly desirable to both reduce cost, and increase efficiency. Within neural progenitors, LIM homeobox transcription factor 1 alpha (Lmx1a) is required for proper development of r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hunt, Cameron P., Fabb, Stewart A., Pouton, Colin W., Haynes, John M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806860/ https://www.ncbi.nlm.nih.gov/pubmed/24194952 http://dx.doi.org/10.1371/journal.pone.0078759

Ejemplares similares

Human pluripotent stem cell derived midbrain PITX3(eGFP/w) neurons: a versatile tool for pharmacological screening and neurodegenerative modeling
por: Watmuff, Bradley, et al.
Publicado: (2015)

ATG8-dependent LMX1B-autophagy crosstalk shapes human midbrain dopaminergic neuronal resilience
por: Jiménez-Moreno, Natalia, et al.
Publicado: (2023)

Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing Progenitors
por: Hedlund, Eva, et al.
Publicado: (2016)

Midbrain dopamine neurons signal aversion in a reward-context-dependent manner
por: Matsumoto, Hideyuki, et al.
Publicado: (2016)

Lmx1a is a master regulator of the cortical hem
por: Iskusnykh, Igor Y, et al.
Publicado: (2023)

Adenovirus Terminal Protein Contains a Bipartite Nuclear Localisation Signal Essential for Its Import into the Nucleus
por: Al-Wassiti, Hareth A., et al.
Publicado: (2021)

Cerebral-Organoid-Derived Exosomes Alleviate Oxidative Stress and Promote LMX1A-Dependent Dopaminergic Differentiation
por: Ji, Xingrui, et al.
Publicado: (2023)

Stimulus-Dependent Adjustment of Reward Prediction Error in the Midbrain
por: Takemura, Hiromasa, et al.
Publicado: (2011)

Transcriptional repression of Plxnc1 by Lmx1a and Lmx1b directs topographic dopaminergic circuit formation
por: Chabrat, Audrey, et al.
Publicado: (2017)

Reward and choice encoding in terminals of midbrain dopamine neurons depends on striatal target
por: Parker, Nathan F., et al.
Publicado: (2016)

An Lmx1b-miR135a2 Regulatory Circuit Modulates Wnt1/Wnt Signaling and Determines the Size of the Midbrain Dopaminergic Progenitor Pool
por: Anderegg, Angela, et al.
Publicado: (2013)

LmxMPK4, a mitogen-activated protein (MAP) kinase homologue essential for promastigotes and amastigotes of Leishmania mexicana
por: Wang, Qiong, et al.
Publicado: (2005)

Site-Specific Phosphorylation of the DNA Damage Response Mediator Rad9 by Cyclin-Dependent Kinases Regulates Activation of Checkpoint Kinase 1
por: Abreu, Carla Manuela, et al.
Publicado: (2013)

Adult Raphe-Specific Deletion of Lmx1b Leads to Central Serotonin Deficiency
por: Song, Ning-Ning, et al.
Publicado: (2011)

Lmx1a-Dependent Activation of miR-204/211 Controls the Timing of Nurr1-Mediated Dopaminergic Differentiation
por: Pulcrano, Salvatore, et al.
Publicado: (2022)

The role of DNA dependent protein kinase in synapsis of DNA ends
por: Weterings, Eric, et al.
Publicado: (2010)

DNA–dependent protein kinase in telomere maintenance and protection
por: Sui, Jiangdong, et al.
Publicado: (2020)

Autophosphorylation and Self-Activation of DNA-Dependent Protein Kinase
por: Kurosawa, Aya
Publicado: (2021)

Human DNA-dependent protein kinase activation mechanism
por: Liang, Shikang, et al.
Publicado: (2023)

LmxM.22.0250-Encoded Dual Specificity Protein/Lipid Phosphatase Impairs Leishmania mexicana Virulence In Vitro
por: Kraeva, Natalya, et al.
Publicado: (2019)

Transcription Factor Lmx1b Negatively Regulates Osteoblast Differentiation and Bone Formation
por: Kim, Kabsun, et al.
Publicado: (2022)

Dose-Dependent and Subset-Specific Regulation of Midbrain Dopaminergic Neuron Differentiation by LEF1-Mediated WNT1/b-Catenin Signaling
por: Nouri, Parivash, et al.
Publicado: (2020)

Activation Mechanism of Protein Kinase B by DNA-dependent Protein Kinase Involved in the DNA Repair System
por: Li, Yuwen, et al.
Publicado: (2008)

DNA-dependent protein kinase and DNA repair: relevance to Alzheimer's disease
por: Kanungo, Jyotshna
Publicado: (2013)

Neural circuits and nicotinic acetylcholine receptors mediate the cholinergic regulation of midbrain dopaminergic neurons and nicotine dependence
por: Xiao, Cheng, et al.
Publicado: (2019)

Regulation of smooth muscle-specific gene expression by cGMP-dependent protein kinase
por: Zhang, Tong, et al.
Publicado: (2009)

Lineage-specific mutation of Lmx1b provides new insights into distinct regulation of suture development in different areas of the calvaria
por: Cabrera Pereira, Angel, et al.
Publicado: (2023)

Association of Transcription Factor Gene LMX1B with Autism
por: Thanseem, Ismail, et al.
Publicado: (2011)

Context-dependent conservation of DNA methyltransferases in bacteria
por: Seshasayee, Aswin Sai Narain, et al.
Publicado: (2012)

Reducing DNA context dependence in bacterial promoters
por: Carr, Swati B., et al.
Publicado: (2017)

Multiple value signals in dopaminergic midbrain and their role in avoidance contexts
por: Rigoli, Francesco, et al.
Publicado: (2016)

Identification of limb-specific Lmx1b auto-regulatory modules with Nail-patella syndrome pathogenicity
por: Haro, Endika, et al.
Publicado: (2021)

Chemokine Receptor Redundancy and Specificity Are Context Dependent
por: Dyer, Douglas P., et al.
Publicado: (2019)

Survival of midbrain dopamine neurons depends on the Bcl2 factor Mcl1
por: Robinson, Edward J., et al.
Publicado: (2018)

Protein phosphatase 1 and phosphatase 1 nuclear targeting subunit-dependent regulation of DNA-dependent protein kinase and non-homologous end joining
por: Zhu, Songli, et al.
Publicado: (2017)

Phosphorylation of polynucleotide kinase/ phosphatase by DNA-dependent protein kinase and ataxia-telangiectasia mutated regulates its association with sites of DNA damage
por: Zolner, Angela E., et al.
Publicado: (2011)

Heparan Sulfates Regulate Axonal Excitability and Context Generalization through Ca(2+)/Calmodulin-Dependent Protein Kinase II
por: Song, Inseon, et al.
Publicado: (2023)

XRCC1 is phosphorylated by DNA-dependent protein kinase in response to DNA damage
por: Lévy, Nicolas, et al.
Publicado: (2006)

DNA Methylation Adjusts the Specificity of Memories Depending on the Learning Context and Promotes Relearning in Honeybees
por: Biergans, Stephanie D., et al.
Publicado: (2016)

DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis
Publicado: (1995)

Cannot write session to /tmp/vufind_sessions/sess_q2unjba7fq1dnoudtnhi0avpo8