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SERF Protein Is a Direct Modifier of Amyloid Fiber Assembly
The inherent cytotoxicity of aberrantly folded protein aggregates contributes substantially to the pathogenesis of amyloid diseases. It was recently shown that a class of evolutionary conserved proteins, called MOAG-4/SERF, profoundly alter amyloid toxicity via an autonomous but yet unexplained mode...
Autores principales: | Falsone, S. Fabio, Meyer, N. Helge, Schrank, Evelyne, Leitinger, Gerd, Pham, Chi L.L., Fodero-Tavoletti, Michelle T., Holmberg, Mats, Dulle, Martin, Scicluna, Benjamin, Gesslbauer, Bernd, Rückert, Hanna-Marie, Wagner, Gabriel E., Merle, David A., Nollen, Ellen A., Kungl, Andreas J., Hill, Andrew F., Cappai, Roberto, Zangger, Klaus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807654/ https://www.ncbi.nlm.nih.gov/pubmed/22854022 http://dx.doi.org/10.1016/j.celrep.2012.06.012 |
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