Mutations in DNA-Binding Loop of NFAT5 Transcription Factor Produce Unique Outcomes on Protein–DNA Binding and Dynamics

[Image: see text] The nuclear factor of activated T cells 5 (NFAT5 or TonEBP) is a Rel family transcriptional activator and is activated by hypertonic conditions. Several studies point to a possible connection between nuclear translocation and DNA binding; however, the mechanism of NFAT5 nuclear tra...

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Detalles Bibliográficos
Autores principales: Li, Minghui, Shoemaker, Benjamin A., Thangudu, Ratna R., Ferraris, Joan D., Burg, Maurice B., Panchenko, Anna R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807822/
https://www.ncbi.nlm.nih.gov/pubmed/23734591
http://dx.doi.org/10.1021/jp403310a

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