Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection

Animal cells harbour multiple innate effector mechanisms that inhibit virus replication. For the pathogenic retrovirus human immunodeficiency virus type-1 (HIV-1), these include widely expressed restriction factors(1) such as APOBEC3 proteins(2), TRIM5α(3), tetherin/BST2(4,5) and SAMHD1(6,7), as wel...

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Detalles Bibliográficos
Autores principales: Goujon, Caroline, Moncorgé, Olivier, Bauby, Hélène, Doyle, Tomas, Ward, Christopher C., Schaller, Torsten, Hué, Stéphane, Barclay, Wendy S., Schulz, Reiner, Malim, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808269/
https://www.ncbi.nlm.nih.gov/pubmed/24048477
http://dx.doi.org/10.1038/nature12542

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