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Coagulation Activation in Children with Sickle Cell Disease Is Associated with Cerebral Small Vessel Vasculopathy

BACKGROUND: Thrombotic complications in Sickle Cell Disease (SCD) arise since infancy, but the role of the coagulation system in children has been poorly explored. To determine its role in the development of clinical complications in childhood we measured coagulation and endothelial parameters in ch...

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Detalles Bibliográficos
Autores principales: Colombatti, Raffaella, De Bon, Emiliano, Bertomoro, Antonella, Casonato, Alessandra, Pontara, Elena, Omenetto, Elisabetta, Saggiorato, Graziella, Steffan, Agostino, Damian, Tamara, Cella, Giuseppe, Teso, Simone, Manara, Renzo, Rampazzo, Patrizia, Meneghetti, Giorgio, Basso, Giuseppe, Sartori, Maria Teresa, Sainati, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808283/
https://www.ncbi.nlm.nih.gov/pubmed/24205317
http://dx.doi.org/10.1371/journal.pone.0078801