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Persistence of EBV Antigen-Specific CD8 T Cell Clonotypes during Homeostatic Immune Reconstitution in Cancer Patients
Persistent viruses are kept in check by specific lymphocytes. The clonal T cell receptor (TCR) repertoire against Epstein-Barr virus (EBV), once established following primary infection, exhibits a robust stability over time. However, the determinants contributing to this long-term persistence are st...
Autores principales: | Iancu, Emanuela M., Gannon, Philippe O., Laurent, Julien, Gupta, Bhawna, Romero, Pedro, Michielin, Olivier, Romano, Emanuela, Speiser, Daniel E., Rufer, Nathalie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808305/ https://www.ncbi.nlm.nih.gov/pubmed/24205294 http://dx.doi.org/10.1371/journal.pone.0078686 |
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