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A Glycolipid Adjuvant, 7DW8-5, Enhances CD8+ T Cell Responses Induced by an Adenovirus-Vectored Malaria Vaccine in Non-Human Primates
A key strategy to a successful vaccine against malaria is to identify and develop new adjuvants that can enhance T-cell responses and improve protective immunity. Upon co-administration with a rodent malaria vaccine in mice, 7DW8-5, a recently identified novel analog of α-galactosylceramide (α-GalCe...
Autores principales: | Padte, Neal N., Boente-Carrera, Mar, Andrews, Chasity D., McManus, Jenny, Grasperge, Brooke F., Gettie, Agegnehu, Coelho-dos-Reis, Jordana G., Li, Xiangming, Wu, Douglass, Bruder, Joseph T., Sedegah, Martha, Patterson, Noelle, Richie, Thomas L., Wong, Chi-Huey, Ho, David D., Vasan, Sandhya, Tsuji, Moriya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808339/ https://www.ncbi.nlm.nih.gov/pubmed/24205224 http://dx.doi.org/10.1371/journal.pone.0078407 |
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