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Role of MicroRNA 1207-5P and Its Host Gene, the Long Non-Coding RNA Pvt1, as Mediators of Extracellular Matrix Accumulation in the Kidney: Implications for Diabetic Nephropathy

Diabetic nephropathy is the most common cause of chronic kidney failure and end-stage renal disease in the Western World. One of the major characteristics of this disease is the excessive accumulation of extracellular matrix (ECM) in the kidney glomeruli. While both environmental and genetic determi...

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Detalles Bibliográficos
Autores principales: Alvarez, M. Lucrecia, Khosroheidari, Mahdieh, Eddy, Elena, Kiefer, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808414/
https://www.ncbi.nlm.nih.gov/pubmed/24204837
http://dx.doi.org/10.1371/journal.pone.0077468

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